ESR11 Project

Selective hydrogenation of amides with supported transition metal nanoparticles
Recruting institution: DTU
Diploma-delivering institutions: DTU, UPS
Thesis co-directors: Anders Riisager (DTU, Lingby, DK), Karine Philippot (LCC, Toulouse, FR)
Secondment host: IFP Energies Nouvelles (FR)

Objectives
Develop new catalysts (mono- and bimetallic) based on supported metal nanoparticles [1] for the hydrogenation of amides reactions [2]. Higher efficiency is expected owing to the high surface/volume ratio provided by the ultra-small nanoparticles produced by the organometallic approach. Apply the best catalytic systems to continuous flow conditions using the SILP thechnology [3]; optionally in combination with scCO2 as substrate carrier for low-volatile substrates.
Expected Results
Obtain nanocatalysts that react under much milder conditions (T≤100°C and P(H2) ≤20 bar) than those reported today, which work under harsh conditions (T~150-300°C ; P(H2)~100-350 bar) and evaluate their recyclability for at least 5 successive runs. Combine the advantage of the catalytic performance of nanocatalysts with those of the SILP technology to perform continuous liquid phase flow catalysis in a fixed bed reactor.

[1] T. Ayvali, K. Philippot, in New Materials for Catalytic Applications, E. Kemnitz and V. Parvulescu (Eds.), Elsevier, 2016, 41-79; C. Amiens, D. Ciuculescu-Pradines, K. Philippot, Coord. Chem. Rev., 2016, 38, 409-432.
[2] A. M. Smith, R. Whyman, Chem. Rev., 2014, 114, 5477-5510. [3] (a) Supported Ionic Liquids: Fundamentals and Applications, R. Fehrmann, A. Riisager, M. Haumann (eds), 2014, Wiley-VHC. (b) A. Riisager and R. Fehrmann, WO2006122563A1 (Wacker Chemie). (c) A. Riisager, R. Fehrmann, J. Xiong and E.J.Garcia-Suarez, WO2011026860A1 (DTU).